In my recent talks, I've often highlighted that the secretions of MSCs are what is behind their therapeutic effect - this is supported by the findings of several publications investigating their paracrine properties. This 2019 paper … [Continue reading]
UC-MSCs clear apoptotic cells (lupus)
Apoptotic cells are cells that have reached the end of their life cycle. They would normally be cleared by other cells the body that recognize an "eat me" signal to suppress them. However, patients with lupus have difficulty clearing those apoptotic … [Continue reading]
Spinal cord injury patients receiving BMMSC show improvements compared to control group
This 2013 study features a treatment group (who received bone marrow mesenchymal stem cells) and a control group (who did not receive cells). 20 patients were in the treatment group and 20 in the control group, for a total of 40 patients with spinal … [Continue reading]
Early study (2008) of bone marrow stem cells for spinal cord injury
Research on the treatment of spinal cord injury with cells from bone marrow aspirate was already ongoing more than a decade ago. This 2008 study followed 8 patients for for 2 years after receiving an average of 90 million CD34 cells directly to the … [Continue reading]
MSCs: A step forward for mitochondrial diseases
Mitochondria are extremely important for cells, as they produce the energy they need to carry out their tasks in a normal, healthy body. So when mitochondria can’t or won’t function as they are supposed to, serious conditions or diseases can … [Continue reading]
Early treatment with BMMSC for spinal cord injury results in long-term benefits
The earlier, the better: in spinal cord injuries, treatment with mesenchymal stem cells may make a difference if applied soon after trauma. In this 2015 Polish case report, a 15 year old girl was treated with bone marrow MSC just 21 days after … [Continue reading]
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